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As actin is pulled, the filaments move approximately 10 nm toward the M-line. This allows further growth, as the smooth muscle tissue grows. It is common for a limb in a cast to show atrophied muscles when the cast is removed, and certain diseases, such as polio, show atrophied muscles. Because DMD is caused by a mutation in the gene that codes for dystrophin, it was thought that introducing healthy myoblasts into patients might be an effective treatment. This may be more of a factor in brief, intense muscle output rather than sustained, lower intensity efforts. As it is broken down, ATP must therefore be regenerated and replaced quickly to allow for sustained contraction. Why such a variety of answers?

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